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The Coronary Artery Disease Market is forecast to show Marginal Growth until 2016
Hyderabad, AP, India (prbd.net) 17/03/2010

"Atherosclerosis Or Coronary Artery Disease (CAD) - Drug Pipeline Analysis and Market Forecasts to 2016"

The coronary artery disease (CAD) market is a highly competitive market and is expected to become more competitive until 2016. Three major patent expiries are expected during the forecast period, Plavix and Lipitor by 2011 and Crestor by 2016. The patient expiries of these blockbuster drugs will trigger generic competition into the CAD market making it more competitive. However, due to the increase in number of CAD patients and the entry of novel therapies will be responsible for a stable growth between 2009 and 2016. The presently marketed products for the treatment of CAD have overall high efficacy and safety standards. The market also has two other modes of treatment, which are coronary artery bypass grafting (CABG) and angioplasty. The CAD mortality rate is very high compared to other diseases due to coronary events associated with CAD, including myocardial infarction (MI), angina and strokes. Therefore, the prevention of such events still remains an untapped area of research and development for pharmaceutical companies to bring novel drugs into the market. It would, therefore, be sufficient for newer entrants to demonstrate a superior efficacy and safety profile in order to capture value in the market from the currently used branded and generic treatments.


GlobalData’s analysis estimates that Darapladib, Anacetrapib, Aliskiren and SCH 530348 are likely to get market approval as these drugs are expected to bring higher efficacy and safety measures in the treatment of CAD. Some of these therapies are also likely to bring changes in the treatment approach, by introducing much needed efficacy in the reduction of the progression of atherosclerosis in CAD patients. These novel therapies would remain market drivers in the future. Increases in the treatment seeking population, prescription rates and the ageing global population are also considered to be important drivers for this market. GlobalData’s analysis shows that the market grew at a compound annual growth rate (CAGR) of 6.5% from $10.5 billion in 2001 to $17.4 billion in 2009. The market is predicted to grow at a marginal CAGR of 0.15% from 2009 and reach a total value of $17.6 billion by 2016. The marginal projected growth rate is primarily attributed to the patent expiries of some of the major marketed products like Lipitor, Crestor and Plavix. The availability of new first-in-class therapies with better safety and efficacy profiles are expected to offset the negative impact of the patent expiry of major drugs and drive the growth of the CAD market in the future.

GlobalData found the current competition in the CAD market to be strong as the market is mainly governed by branded and generic products that have comparable safety and efficacy profiles. This apart, major revenues for this market are generated by statins, antiplatelet and anticoagulants, which are prescribed in addition to beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, and angiotensin II receptor blockers (ARBs), to achieve superior treatment in patients. The antiplatelet and renin inhibitors (a new class of molecule) market is in itself set to witness a remarkable growth rate with the approval of newer drugs. The entry of these newer classes of drugs will undoubtedly accelerate the growth of the CAD market and also offset the negative impact of the patent expiry of major products. This would, in turn, start a race for a new class of pharmaceuticals with effective mechanisms of action. Merck & Co., Inc. is expected to lead sales in the CAD market with the introduction of Anacetrapib and SCH 530348 in the next few years. However, other products, such as Darapladib and Aliskiren, are also likely to propel the growth of the market.

GlobalData, the industry analysis specialist’s new report, “Atherosclerosis Or Coronary Artery Disease (CAD) - Drug Pipeline Analysis and Market Forecasts to 2016” is an essential source of information and analysis on the global coronary artery disease (CAD) market. The report identifies the key trends shaping and driving the market, and provides insight into the prevalent competitive landscape and the emerging players expected to bring a significant shift in the positioning of the existing market leaders. Most importantly, the report provides valuable insight into the pipeline products within the global CAD therapeutics sector.

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